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• Rudge JS, Silver J. Inhibition of neurite outgrowth on astroglial scars in vitro.
• On one aspect, the lesions have been concomitantly infused with N-CAM or with one of the N-CAM-related molecules.
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Neural Cell Adhesion Molecule N

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I need help in completing these tasks, currently. This is easy stage and if you are professional in c++, may be accomplished in quickly. Janeczko K. The proliferative response of astrocytes to injury in neonatal rat brain. A combined immunocytochemical and autoradiographic examine.

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Immunoelectron Microscopic Localization Of Neural Cell Adhesion Molecules L1, N

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After a penetrating lesion within the central nervous system, astrocytes enlarge, divide, and take part in creating an surroundings that adversely impacts neuronal regeneration. We have just lately proven that the neural cell adhesion molecule (N-CAM) partially inhibits the division of early postnatal rat astrocytes in vitro. Animals were lesioned in the cerebral cortex, hippocampus, or striatum with a Hamilton syringe and needle at defined stereotaxic positions. On one facet, the lesions have been concomitantly infused with N-CAM or with one of the N-CAM-related molecules. As a management, a peptide of the same composition because the N-CAM decapeptide however of random sequence was infused on the contralateral aspect of the mind. The inhibition was greatest within the cortical lesion websites (approximately 50%) and was less pronounced in the hippocampus (approximately 25%) and striatum (approximately 20%). Two weeks after the lesion, the cerebral cortical sites infused with N-CAM continued to exhibit a significantly smaller population of dividing astrocytes than the sites on the opposite side.

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